From Chapter 1:
Who first smoked a pipe of tobacco in England? The honour is divided among several claimants. It has often been stated that Captain William Middleton or Myddelton (son of Richard Middleton, Governor of Denbigh Castle), a Captain Price and a Captain Koet were the first who smoked publicly in London, and that folk flocked from all parts to see them; and it is usually added that pipes were not then invented, so they smoked the twisted leaf, or cigars. This account first appeared in one of the volumes of Pennant's "Tour in Wales." But the late Professor Arber long ago pointed out that the remark as to the mode of smoking by cigars and not by pipes was simply Pennant's speculation. The authority for the rest of the story is a paper in the Sebright MSS., which, in an account of William Middleton, has the remark: "It is sayed, that he, with Captain Thomas Price of Plâsyollin and one Captain Koet, were the first who smoked, or (as they called it) drank tobacco publickly in London; and that the Londoners flocked from all parts to see them." No date is named, and no further particulars are available.

From Chapter 6:
Other well-known men of the late seventeenth century were "tobacconists" in the old sense of the word. Sir Isaac Newton is said to have smoked immoderately; and a familiar anecdote represents him as using for the purposes of a tobacco-stopper, in a fit of absent-mindedness, the little finger of a lady sitting beside him, whom he admired, but the truth of this legend is open to doubt. Thomas Hobbes, who lived to be ninety (1588-1679), was accustomed to dine at 11 o'clock, after which he smoked a pipe and then lay down and took a nap of about half an hour. No doubt he would have attributed the length of his days to the regularity of his habits. Izaak Walton, who also lived to be ninety, as the lover of the placid and contemplative life deserved to do, loved his pipe, though he seldom mentions smoking in the "Compleat Angler." Sir Samuel Garth, poet and physician, once known to fame as the author of "The Dispensary," was another pipe-lover, as is shown by his verses quoted at the head of this chapter. Dudley, the fourth Lord North, began to smoke in 1657, and, says Dr. Jessopp, "the habit grew upon him, the frequent entries for pipes and tobacco showing that he became more and more addicted to this indulgence. Probably it afforded him some solace in the dreadful malady from which he suffered so long."