From Chapter 1:
Perhaps the most likely scene of Raleigh's first experiments in the art of smoking was Durham House, which stood where the Adelphi Terrace and the streets between it and the Strand now stand. This was in the occupation of Sir Walter for twenty years (1583-1603), and he was probably resident there when Hariot returned from Virginia to make his report and instruct his employer in the management of a pipe. Walter Thornbury, in his "Haunted London," referring to the story of the servant throwing the ale over his smoking master, says: "There is a doubtful old legend about Raleigh's first pipe, the scene of which may be not unfairly laid at Durham House, where Raleigh lived." The ale story is mythical, but it is highly probable that Sir Walter's first pipes were smoked in Durham House. Dr. Brushfield quotes Hepworth Dixon, in "Her Majesty's Tower," as drawing "an imaginary and yet probable picture of him and his companions at a window of this very house, overlooking the 'silent highway':

From Chapter 6:
The practice of selling tobacco in small paper packets was common, and moralists naturally had something to say about the fate of an author's work, when the leaves of his books found their ultimate use as wrappers for the weed. "For as no mortal author," says Addison, "in the ordinary fate and vicissitude of things, knows to what use his works may, some time or other, be applied, a man may often meet with very celebrated names in a paper of tobacco. I have lighted my pipe more than once with the writings of a prelate."