From Chapter 4:
From the various entries in the "Diary" relating to the purchase of tobacco, it seems clear that there was no shop in Exeter devoted specially or exclusively to the sale of the weed. Hayne bought his supplies from four of the leading goldsmiths of the city, who can be identified by the fact that he had dealings with them in their own special wares, also from two drapers, one grocer, and four other tradesmen (on a single occasion each) whose particular occupations are unknown.

From Chapter Chapter 8:
Cowper then goes on to attack tobacco in lines which show how unpopular smoking at that date was with ladies, and which have since often been quoted by anti-tobacconists with grateful appreciation:

Pernicious weed! whose scent the fair annoys,
Unfriendly to society's chief joys,
Thy worst effect is banishing for hours
The sex whose presence civilizes ours;
Thou art indeed the drug a gardener wants,
To poison vermin that infest his plants,
But are we so to wit and beauty blind,
As to despise the glory of our kind,
And show the softest minds and fairest forms
As little mercy as the grubs and worms?

Notwithstanding this "satiric wipe," it is not likely that Cowper would have had much sympathy with John Wesley, who, in his detestation of what had been his father's solace at Epworth, forbade his preachers either to smoke or to take snuff.