From Chapter 3:
Another tract which may be classed with Venner's "Treatise" was the "Nepenthes or the Vertues of tobacco," by Dr. William Barclay, which was published at Edinburgh in 1614. This is sometimes referred to and quoted, as by Fairholt, as if it were a whole-hearted defence of tobacco-taking. But Barclay enlarges mainly on the medicinal virtues of the herb. "If Tabacco," he says, "were used physically and with discretion there were no medicament in the worlde comparable to it"; and again: "In Tabacco there is nothing which is not medicine, the root, the stalke, the leaves, the seeds, the smoake, the ashes." The doctor gives sundry directions for administering tobacco—"to be used in infusion, in decoction, in substance, in smoke, in salt." But Barclay clearly does not sympathize with its indiscriminate use for pleasure. "As concerning the smoke," he says, "it may be taken more frequently, and for the said effects, but always fasting, and with emptie stomack, not as the English abusers do, which make a smoke-boxe of their skull, more fit to be carried under his arme that selleth at Paris dunoir a noircir to blacke mens shooes then to carie the braine of him that can not walke, can not ryde except the Tabacco Pype be in his mouth." He goes on to say that he was once in company with an English merchant in Normandy—"betweene Rowen and New-haven"—who was a merry fellow, but was constantly wanting a coal to kindle his tobacco. "The Frenchman wondered and I laughed at his intemperancie."

From Chapter 8:
No doubt smoking had its ups and downs at the Universities apart from the set of the main current of fashion. We learn from the invaluable Gunning that at Cambridge about 1786 smoking was going "out of fashion among the junior members of our combination-rooms, except on the river in the evening, when every man put a short pipe in his mouth." "I took great pains," he adds, "to make myself master of this elegant accomplishment, but I never succeeded, though I used to renew the attempt with a perseverance worthy of a better cause." About the same time Dr. Farmer was Master of Emmanuel and the Master was an inveterate smoker. Gunning says that Emmanuel parlour under Farmer's presidency was always open to those who loved pipes and tobacco and cheerful conversation—a very natural collocation of tastes. Farmer's silver tobacco-pipe is still preserved in his old college, while Porson's japanned snuff-box is at Trinity.