From Chapter 1:
The truth probably is that whoever actually smoked the first pipe, it was Raleigh who brought the practice into common use. It is highly probable, also, that Raleigh was initiated in the art of smoking by Thomas Hariot. This was made clear, I think, by the late Dr. Brushfield in the second of the valuable papers on matters connected with the life and achievements of Sir Walter, which he contributed under the title of "Raleghana" to the "Transactions" of the Devonshire Association. Hariot was sent out by Raleigh for the specific purpose of inquiring into and reporting upon the natural productions of Virginia. He returned in 1586, and in 1588 published the results of his researches in a thin quarto with an extremely long-winded title beginning "A briefe and true report of the new found land of Virginia" and continuing for a further 138 words.

From Chapter 6:
The practice of selling tobacco in small paper packets was common, and moralists naturally had something to say about the fate of an author's work, when the leaves of his books found their ultimate use as wrappers for the weed. "For as no mortal author," says Addison, "in the ordinary fate and vicissitude of things, knows to what use his works may, some time or other, be applied, a man may often meet with very celebrated names in a paper of tobacco. I have lighted my pipe more than once with the writings of a prelate."