From Chapter 1:
"'It requires no effort of the fancy to picture these three men [Shakespeare, Bacon and Raleigh] as lounging in a window of Durham House, puffing the new Indian weed from silver bowls, discussing the highest themes in poetry and science, while gazing on the flower-beds and the river, the darting barges of dame and cavalier, and the distant pavilions of Paris garden and the Globe.'" This is a pure "effort of the fancy" so far as Bacon and Shakespeare are concerned. Shakespeare's absolute silence about tobacco forbids us to assume that he smoked; but of Raleigh the picture may be true enough. The house had, as Aubrey tells us, "a little turret that looked into and over the Thames, and had the prospect which is as pleasant perhaps as any in the world"; and it would be strange indeed if the owner of the noble house did not often smoke a contemplative pipe in the window of that pleasant turret.

From Chapter 6:
After King William III was settled on the throne the sum of £600,000 was paid to the Dutch from the English exchequer for money advanced in connexion with his Majesty's expedition, and this amount was paid off by tobacco duties. Granger long ago remarked that most of the eminent divines and bishops of the day contributed very practically to the payment of this revolutionary debt by their large consumption of tobacco. He mentions Isaac Barrow, Dr. Barlow of Lincoln, who was as regular in smoking tobacco as at his meals, and had a high opinion of its virtues, Dr. Aldrich, "and other celebrated persons who flourished about this time, and gave much into that practice." One of the best known of these celebrated persons was Gilbert Burnet, Bishop of Salisbury from 1689, and historian of his own times. He had the reputation of being an inveterate smoker, and was caricatured with a long clay stuck through the brim of the shovel hat, on the breadth of which King William once made remark. The bishop replied that the hat was of a shape suited to his dignity, whereupon the King caustically said, "I hope that the hat won't turn your head."