From Chapter 1:
Another Elizabethan who is often said to have smoked the first pipe in England is Ralph Lane, the first Governor of Virginia, who came home with Drake in 1586. Lane is said to have given Sir Walter Raleigh an Indian pipe and to have shown him how to use it. There is no original authority, however, for the statement that Lane first smoked tobacco in England, and, moreover, he was not the first English visitor to Virginia to return to this country. One Captain Philip Amadas accompanied Captain Barlow, who commanded on the occasion of Raleigh's first voyage of discovery, when the country was formally taken possession of and named Virginia in honour of Queen Elizabeth. This was early in 1584. The two captains reached England in September 1584, bringing with them the natives of whom King James I, in his "Counter-blaste to Tobacco," speaks as "some two or three Savage men," who "were brought in, together with this Savage custome," i.e. of smoking. It is extremely improbable that Captains Amadas and Barlow, when reporting to Raleigh on their expedition, did not also make him acquainted with the Indian practice of smoking. This would be two years before the return of Ralph Lane.

From Chapter 5:
At the time of the Great Plague all kinds of nostrums were sold and recommended as preservatives or as cures. Most of these perished with the occasion that called them forth; but the names of some have been preserved in a rare quarto tract which was published in the Plague year, 1665, entitled "A Brief Treatise of the Nature, Causes, Signes, Preservation from and Cure of the Pestilence," "collected by W. Kemp, Mr. of Arts." In the list of devices for purifying infected air it is stated that "The American Silver-weed, or Tobacco, is very excellent for this purpose, and an excellent defence against bad air, being smoked in a pipe, either by itself, or with Nutmegs shred, and Rew Seeds mixed with it, especially if it be nosed"—which, I suppose, means if the smoke be exhaled through the nose—"for it cleanseth the air, and choaketh, suppresseth and disperseth any venomous vapour." Mr. Kemp warms to his subject and proceeds with a whole-hearted panegyric that must be quoted in full: "It hath singular and contrary effects, it is good to warm one being cold, and will cool one being hot. All ages, all Sexes, all Constitutions, Young and Old, Men and Women, the Sanguine, the Cholerick, the Melancholy, the phlegmatick, take it without any manifest inconvenience, it quencheth thirst, and yet will make one more able, and fit to drink; it abates hunger, and yet will get one a good stomach; it is agreeable with mirth or sadness, with feasting and with fasting; it will make one rest that wants sleep, and will keep one waking that is drowsie; it hath an offensive smell to some, and is more desirable than any perfume to others; that it is a most excellent preservative, both experience and reason do teach; it corrects the air by Fumigation, and it avoids corrupt humours by Salivation; for when one takes it either by Chewing it in the leaf, or Smoaking it in the pipe, the humors are drawn and brought from all parts of the body, to the stomach, and from thence rising up to the mouth of the Tobacconist, as to the helme of a Sublimatory, are voided and spitten out."