From Chapter 1:
The form and make of the first pipe is a matter I do not propose to go into here; but in connexion with the first pipe smoked in this country Aubrey's interesting statements must be given. Writing in the time of Charles II, he said that he had heard his grandfather say that at first one pipe was handed from man to man round about the table. "They had first silver pipes; the ordinary sort made use of a walnut shell and a straw"—surely a very unsatisfactory pipe. Tobacco in those earliest days, he says, was sold for its weight in silver. "I have heard some of our old yeomen neighbours say that when they went to Malmesbury or Chippenham Market, they culled out their biggest shillings to lay in the scales against the tobacco."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."